Thursday, June 11, 2015

PRINCIPLES OF RATIONAL ANTIBIOTIC USE



* Microorganisms-suspected etiologic agent and patterns of local antimicrobial susceptibility
* Host factors-age, pregnancy, concomitant disease (s), host defense mechanism
* Site of infection, severity of infection
* Drug factors and previous antibiotics, etc.
* Appropriate specimens for Gram staining,
 culture and sensitivity test
should be taken prior to antibiotic treatment

Prevention of irrational prescribing

*To prevent irrational prescribing the following measures should be taken- a) making correct diagnosis; b) limiting the number of drugs; c) encouraging the availability of essential drugs; d) providing adequate training, drug information and Standard treatment guideline (STG) to the prescribers through continuing education, incorporating the concept of essential drugs; e) teaching of rational prescribing into the curricula of medicine, pharmacy, dentistry and nursing; and f) finally providing effective public education of the consumers and on public.

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